SEDIMENTATION FIELD-FLOW FRACTIONATION APPLICATIONS (SEDIMENTATION FFF)
Sedimentation FFF is the benchmark in high resolution
separation of nanoparticles, such as emulsions, latexes and any colloids
dispersed in liquids or even emulsions. Sedimentation FFF in general is ideal for
applications in biomedical, biotechnology, polymer, material and
environmental science.
Characterization of Emulsions
Sedimentation FFF is ideally suited for separation and characterization of
emulsions and drug delivery vehicles. It provides high resolution separation
under gentle, low shear conditions. As an analytical-scale, elution-based
technique, the size information is provided along with the separation. Thus
the size distribution is a direct measurement, free from any assumptions. In
comparison with other particle sizing techniques and any chromatographic
separation techniques, Sedimentation FFF can separate sub-micron sized
emulsion droplets of any density. The figure shows that Sedimentation FFF
can give an insight into kinetics of emulsions and how they alter with time
under certain conditions.
Characterization of Soils
The characterization of soil colloids with Sedimentation FFF coupled to
ICP-MS gives the particles size information and at the same time the
complete elemental distribution in the different size fraction can be
determined. As an example, the figure shows the relative mass distribution
determined by UV detection and the distribution of Al and Fe. Shown results
have been published by J. F. Ranville1, R. Beckett2, and D. J.
Chittleborough3, 1. Dept. of Chemistry and Geochemistry, Colorado School of
Mines, Golden, USA; 2. Water Studies Centre, Monash University, Clayton,
Australia; 3. Dept. of Soil Science, University of Adelaide, Glen Osmond,
Australia.
For more information about Sedimentation FFF contact Postnova Analytics via
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Flow FFF | Asymmetrical Flow Field Flow Fractionation | Thermal FFF | Sedimentation FFF