FLOW FFF PRINCIPLE

In Flow FFF the separation force is generated by a cross flow field which is acting perpendicular to the channel flow. The cross flow in Flow FFF is generated by a pump and is passing through the Flow FFF channel. The cross flow in Flow FFF enters the Flow FFF channel via a porous frit on top of the channel and leaves the Flow FFF channel via a semi-permeable membrane at the bottom of the channel, which is placed on another porous frit. The membrane pores size prevents the sample to pass through, but allows the solvent to exit the Flow FFF channel easily. The sample fractions are eluted out of the Flow FFF channel in direction to the detectors by the main channel flow.




FLOW FFF APPLICATIONS

Flow FFF has a very broad application range and can be used for variety of samples. The analytes which successfully have been characterized with Flow FFF are coming from biotechnology, pharmaceutical, chemical, polymer, environmental and nanoparticle applications. Some of them are proteins, aggregates, peptides, viruses, liposomes, paints, silica particles, latices, polyelectrolytes, polyolefins and many more.




For more information about Flow FFF contact Postnova Analytics via telephone, fax, email or visit our homepage www.postnova.com !

 

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Flow FFF  |  Asymmetrical Flow Field Flow Fractionation  |  Thermal FFF  |  Sedimentation FFF